| abstract
| - Overlap refers to the period of time when the effect of one insulin shot is diminishing and the next insulin shot is taking effect. Caregivers can purposefully manage overlap to increase the effect of insulin on their pets' blood glucose levels and thus hold the curve of their blood glucose levels fairly flat. Suppose a cat gets an insulin shot every 12 hours, gets 15 hours duration from each shot, and is on an insulin that has a three hour onset. During the 3 hours after each insulin shot, there will be two insulin shots working to reduce blood glucose levels: the diminishing previous shot and the rising current shot. This may mean that the ongoing insulin dose should be less than if no overlap was used. Using overlap safely and effectively requires significant information about and analysis of how a particular insulin works in your pet (its duration, onset, and peak) and how feeding and other forces (such as exercise or sleep) affect your pets' blood glucose levels. Using overlap may result in diminished insulin needs as your pet's blood glucose levels are reduced from the diminishing effect of the previous shot, and possibly also from the carryover effects of previous shots. Purposeful use of overlap is considered an advanced approach because it usually requires the administration of insulin at blood glucose levels below the renal threshold, or at least lower than some people are willing to administer the next shot. Maximum use of overlap involves administering the next insulin shot at blood glucose nadir, when the effect of the previous shot is at its peak. This technique, ideal in theory, can be dangerous in practise -- you must be sure that the previous shot is about to diminish, which depends on the insulin's action profile in this animal being very predictable. Waiting until the glucose reading has started to rise a bit is more reliable.
* The link below is to a discussion on the Feline Diabetes Message Board about the use of overlap.
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* See also the discussion of tight regulation. Also, overlap is not the same as carryover.
- Mou ichido dake de ii kiseki okite yoKako ni nakushita kioku no peeji o torimodosu chikara o Yami o tsuranuku shinjiru kokoro tamashii nemuru basho sagashite Mabataki dekinai surudoi gankou o moyasuHikari to kage no futatsu no kokoro kurisutaru ni utsuru mirai e Ima ugokidasu akaku minagiru eyes Tagai no kizu o nameau hibi ni owari o tsugete shizuka ni tachiagaru Chiisa na akari tomoshita yoru no kimi to kawashita yakusoku mamorinuku Kasumu shinkirou ga kimi o miseru yo Susunda saki ni nani ga okite mo make wa shinai kakugo de Kiseki wa okoru shinjiru kokoro mukae ni kita shouri no megami ga Subete o taosu donna kabe ni mo hirumanaiMayoitsuzukeru futatsu no kokoro iroaseru koto nai sekai e Ima kagayaku yo kasanariatta EYES! Shizumu taiyou ni tsuki ga tokeru yo Kako ni nakushita kioku no peeji o torimodosu chikara o… Yami o tsuranuku shinjiru kokoro tamashii nemuru basho sagashite Mabataki dekinai surudoi gankou o moyasu Hikari to kage no futatsu no kokoro kurisutaru ni utsuru mirai e Ima ugokidasu akaku minagiru eyes Kasanariau EYES! |-| English= Light, so bright that it can’t be hidden, shatters the silence and revives in this world The parched ground, quaking violently, contends with sparks, betting its life Just once more will be enough, make a miracle happen For the power to recover the pages of memories lost in the past The believing heart penetrates the darkness, searching for the place where its soul rests Its unblinking, sharp gaze gleams The 2 hearts of light and shadow head toward the future reflected in the crystal Now eyes brimming in red will fall into motion I announce the end to the days of licking each other’s wounds and quietly stand up I’ll always keep the promise I made with you on the night when we lit the tiny light A hazy mirage projects an image of you No matter what happens beyond where I go, I’m determined to never lose The heart believes in miracles, and the goddess of victory who came to greet it will defeat everything, undaunted by the strong and powerful The 2 hearts that continue to wander head toward an unfading world Now overlapping eyes will shine The moon melts into the setting sun For the power to recover the pages of memories lost in the past The faithful heart penetrates the darkness, searching for the place where its soul rests Its unblinking, sharp gaze gleams The 2 hearts of light and shadow head toward the future reflected in the crystal Now eyes brimming in red will fall into motion Eyes will overlap
- To overlap is to coexist with another effect or modifier in the same area or on the same target. Bonuses that do not stack with each other overlap instead, such that only the largest bonus provides its benefit.
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