This special half-hour FAMILY GUY tribute showcases the outrageous antics of the Griffin family and celebrates the side-splitting, irreverent humor of the fan-favorite animated series. Some of the funniest moments, satirical spoofs and musical numbers of the past 100 episodes are revisited. MacFarlane also interviews people on their opinions of the show.
The episode aired before the "officially" celebrated 100th episode, "Stewie Kills Lois".