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| rdfs:label
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| dbkwik:resource/2sEMAEJEKAepi0HDgdGAaw==
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| dbkwik:resource/57jW2McNGlE9pqjtgT9qcQ==
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| dbkwik:resource/QseLpQRy423bxxL2KmhCog==
| - Somatostatin has been shown to block the release of numerous vasoactive peptides, including Calcitonin Gene-Related Peptide and vasoactive intestinal polypeptide e et al.. Neurons containing somatostatin are found in the regions of the central and peripheral nervous system involved in nociception, such as peripheral sensory fibres, dorsal horn of the spinal cord, trigeminal nucleus caudalis, periaqueductal gray and the hypothalamus .
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Fassler JE, O'Dorisio TM, Mekhjian HS, Gaginella TS Octreotide inhibits increases in shortcircuit
current induced in rat colon by VIP, substance P, serotonin and aminophylline. Regul Pept
29:189-97.
Helyes Z, Pintér E, Németh J, Kéri G, Thán M, Oroszi G, Horváth A, Szolcsányi J Antiinflammatory
effect of synthetic somatostatin analogues in the rat. Br J Pharmacol 134 :1571-9.
Schindler M, Sellers LA, Humphrey PP, Emson PC Immunohistochemical localization of the
somatostatin SST2 receptor in the rat brain and spinal cord. Neuroscience. 76:225-40.
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| dbkwik:resource/cOQ63AVwiZYf3UUTa8fbjA==
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| dbkwik:resource/eDhPLpw7o8B5wk3WJ-2kTA==
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| dbkwik:resource/p9TOJUtbeeejfnk5AAQHUg==
| - Somatostatin, an endogenously occurring 14–amino acid peptide, has been shown to inhibit the release of numerous vasoactive peptides, including CGRP19 and VIP.20
[page 491]
Neurons
containing somatostatin are found in the regions
of the central and peripheral nervous system involved
in nociception, such as peripheral sensory fibers, dorsal
horn of the spinal cord, trigeminal nucleus caudalis,
periaqueductal gray, and the hypothalamus.31,32
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19. Helyes Z, Pinter E, Nemeth J, et al. Anti-inflammatory effect
of synthetic somatostatin analogues in the rat. Br J Pharmacol
2001;134:1571–1579.
20. Fassler JE, O’Dorisio TM, Mekhjian HS, Gaginella TS. Octreotide
inhibits increases in short-circuit current induced in rat
colon by VIP, substance P, serotonin and aminophylline. Regul
Pept 1990;29:189 –197.
31. Krisch B. Hypothalamic and extrahypothalamic distribution of
somatostatin-immunoreactive elements in the rat brain. Cell
Tissue Res 1978;195:499 –513.
32. Schindler M, Holloway S, Hathway G, et al. Identification of
somatostatin sst2 receptor expressing neurones in central regions
involved in nociception. Brain Res 1998;798:25–35.
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| dbkwik:resource/rhO74gMtkkCwMnnTXRSfyw==
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| dbkwik:resource/svXw5xiEpS-Kv-aSR_SE7w==
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| dbkwik:de.vronipla...iPageUsesTemplate
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| Quelle
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| dbkwik:resource/XhOMK2reAaqeAKQ0pQhkhA==
| - Also the passages after the here documented passage can be found in the source, but the match seems to be somewhat better with another paper by the same author, see Clg/Fragment_024_08.
The source is given further down at the end of the paragraph but without indication that the whole paragraph is taken from it including several references to the literature.
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