Microscopic polyangitis is an autoimmune disease that affects the small blood vessels of the body. Although its triggers are poorly understood, it is linked to the production of an antibody, p-ANCA, that affects those particular blood vessels. It can present with a prosaic constellation of symptoms including fever, loss of appetite, weight loss, fatigue and, in serious cases, kidney failure. Like most autoimmune diseases, there is no cure for the condition, but a course of high dose prednisone or cyclophosphamide can alleviate the symptoms and slow the progression of the disease.
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| - Microscopic polyangitis is an autoimmune disease that affects the small blood vessels of the body. Although its triggers are poorly understood, it is linked to the production of an antibody, p-ANCA, that affects those particular blood vessels. It can present with a prosaic constellation of symptoms including fever, loss of appetite, weight loss, fatigue and, in serious cases, kidney failure. Like most autoimmune diseases, there is no cure for the condition, but a course of high dose prednisone or cyclophosphamide can alleviate the symptoms and slow the progression of the disease.
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mortalityrate
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symptom
| - Fever, anorexia, weight loss, fatigue, kidney failure
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treatment
| - Steroids, cyclophosphamide and plasmapheresis
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abstract
| - Microscopic polyangitis is an autoimmune disease that affects the small blood vessels of the body. Although its triggers are poorly understood, it is linked to the production of an antibody, p-ANCA, that affects those particular blood vessels. It can present with a prosaic constellation of symptoms including fever, loss of appetite, weight loss, fatigue and, in serious cases, kidney failure. Like most autoimmune diseases, there is no cure for the condition, but a course of high dose prednisone or cyclophosphamide can alleviate the symptoms and slow the progression of the disease.
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