As it is a one-handed projectile, the rune throwing axe can be wielded with a shield for protection or an off-hand weapon for offence.
They can be smithed with a Smithing level of 92 or higher from one runite bar, which produces five throwing axes. It can also be obtained by buying it from the Tribal Weapons store at the Ranging Guild, looting from a ninja impling, or trading with another player. As it is a one-handed projectile, the rune throwing axe can be wielded with a shield for protection or an off-hand weapon for offence. Rune throwing axes are seldom used as a primary weapon, due to their slow attack speed, but they can deal decent damage to make up for this.