N,N-Dimethyltryptamine (DMT) is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT during normal metabolism. The natural function of its widespread presence remains undetermined. Structurally, DMT is analogous to the neurotransmitter serotonin (5-HT), the hormone melatonin, and other psychedelic tryptamines, such as 5-MeO-DMT, bufotenin, and psilocin (the active metabolite of psilocybin).
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| - N,N-Dimethyltryptamine (DMT) is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT during normal metabolism. The natural function of its widespread presence remains undetermined. Structurally, DMT is analogous to the neurotransmitter serotonin (5-HT), the hormone melatonin, and other psychedelic tryptamines, such as 5-MeO-DMT, bufotenin, and psilocin (the active metabolite of psilocybin).
- N,N-Dimethyltryptamin, kurz DMT, ist ein sehr starkes Psychedelikum mit einer kurzzeitigen Wirkung. Es ist ein Tryptamin-Alkaloid, welches sich insbesondere in vielen Pflanzen und dem Hautdrüsensekreten einiger Kröten findet und in geringen Konzentrationen in der Natur, insbesondere auch dem menschlichen Körper, fast allgegenwärtig erscheint. In Südamerika hat die entheogene Nutzung von DMT-haltige Pflanzen und Zubereitungen, wie Ayahuasca, Ebena bzw. Yopo (Anadenanthera peregrina), Jurema(Mimosa hostillis) oder des Talgmuskatnussbaums (Virola sebifera), eine weite Verbreitung.
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| - *Dimethyltryptamin
*Nigerin
*Nigerina
*Desoxybofotenin
*2--N,N-dimethylethanamin
*Bewusstseinsmolekül
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| abstract
| - N,N-Dimethyltryptamin, kurz DMT, ist ein sehr starkes Psychedelikum mit einer kurzzeitigen Wirkung. Es ist ein Tryptamin-Alkaloid, welches sich insbesondere in vielen Pflanzen und dem Hautdrüsensekreten einiger Kröten findet und in geringen Konzentrationen in der Natur, insbesondere auch dem menschlichen Körper, fast allgegenwärtig erscheint. In Südamerika hat die entheogene Nutzung von DMT-haltige Pflanzen und Zubereitungen, wie Ayahuasca, Ebena bzw. Yopo (Anadenanthera peregrina), Jurema(Mimosa hostillis) oder des Talgmuskatnussbaums (Virola sebifera), eine weite Verbreitung. DMT wird im Körper schnell durch Monoaminooxidasen (MAO) abgebaut, weshalb es bei oralem Applikationsweg wirkungslos ist und auch sonst nur für wenige Minuten wirkt. Um eine längere oder orale Wirksamkeit zu ermöglichen wird DMT oft mit MAO-Hemmern (MAOIs) kombiniert.
- N,N-Dimethyltryptamine (DMT) is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT during normal metabolism. The natural function of its widespread presence remains undetermined. Structurally, DMT is analogous to the neurotransmitter serotonin (5-HT), the hormone melatonin, and other psychedelic tryptamines, such as 5-MeO-DMT, bufotenin, and psilocin (the active metabolite of psilocybin). In some cultures DMT is ingested as a psychedelic drug (in either extracted or synthesized forms). When DMT is inhaled or consumed, depending on the dose, its subjective effects can range from short-lived milder psychedelic states to powerful immersive experiences, which include a total loss of connection to conventional reality, which may be so extreme that it becomes ineffable. DMT is also the primary psychoactive in ayahuasca, an Amazonian Amerindian brew employed for divinatory and healing purposes. Pharmacologically, ayahuasca combines DMT with an MAOI, an enzyme inhibitor that allows DMT to be orally active.
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