Holcomb was named Miami University's head football coach for the 1942 season succeeding Frank Wilton. His first team went 3–6 which equaled the number of wins of the three previous years for the Redskins. The next year Holcomb and the Redskins posted a winning record of 7–2–1. This team was dominated by defense, only allowing their opponents to score in double digits twice; A 34–12 win over Bradley University and a 35–0 blow out loss to Arkansas A&M. In his two years as Miami’s head coach he compiled an overall record of 10–9–1. He left Miami to become an assistant coach for Earl Blaik at the United States Military Academy. He was replaced as Redskins coach by future Pro and College Football Hall of Fame coach Sid Gillman who was one of Holcomb's top assistant coaches.