Like previous film incarnations of Swamp Thing, the animated series rejects the popular Alan Moore revision of Swamp Thing's origin and portrays him with his original origin as a man turned into a plant-like entity. Anton Arcane takes the role of the main villain responsible for Alec Holland's transformation into Swamp Thing. Arcane is backed by his gang of Un-Men: Dr. Deemo, Weedkiller, and Skinman. Swamp Thing also has two friends named Tomahawk and Bayou Jack. Tomahawk is Native American not to be confused with the DC/Vertigo character, Thomas Hawk, who was a soldier in the American Revolution rescued by Native Americans. Bayou Jack is a Vietnam veteran.