abstract
| - Due to the player using Eleanor, he or she will have access to the newly-introduced Big Sister weapons, as well some Big Daddy weapons from BioShock 2. The player an also do a hard melee attack, while not dealing the same amount of damage that in BioShock 2, it's much faster. Every weapons now has 4 kinds of Ammunition, the fourth being accessed by clicking the left stick.
* Syringe: Replaces the Wrench from the original BioShock. It will deal a great amount of damage, and can recollect a little amount of ADAM from some Splicers (5+).
* Harpoon: Replaces the Drill from BioShock 2. Players will be able to spin it, and even launch it, dealing a high amount of damage.
* Big Sister Rivet Gun: Replaces the Rivet Gun from BioShock 2. It's a new and now standard Big Sister weapon. It's a smaller version of the normal Rivet Gun, however, it deals the same amount of damage.
* Big Sister Machine Gun: Replaces the Gatling Gun. It was manufactured by Big Mother's followers, as a standard weapon for the Big Sisters.
* Shotgun: The double-barreled Shotgun from BioShock 2.
* Big Sister Grenade Launcher: Replaces the Launcher from BioShock 2. It was also manufactured by Big Mother's followers.
* Big Sister Spear Gun: A faster-firing version of the Spear Gun from BioShock 2.
* Hack Tool: The Hack Tool from BioShock 2.
* Chemical Launcher: Replaces the Chemical Thrower from BioShock.
* Research Camera: The Research Camera fom BioShock 2.
* Elephant Gun: Originally available in the BioShock 2 Multiplayer. It's a a slow-firing, slow-reloading, but extremely accurate two-shot weapon, allowing the user to score one-hit kills with a headshot.
* Nail Gun: Originally available in the BioShock 2 Multiplayer. This weapon has a short delay before firing, but afterward, has the highest rate of fire of any weapon.
* Judgement: Nikolai's creation, a cross between the Shotgun and the Machine gun to become an "AA-12" style weapon. It is surprisingly accurate and lethal, but it is so heavy, Eleanor cannot run with it equipt, and her agility is hampered dramatically.
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