About: Prednisolone   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : 134.155.108.49:8890 associated with source dataset(s)

Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Prednisolone can also be used as an immunosuppressive drug for organ transplants and in cases of adrenal insufficiency (Addison's).

AttributesValues
rdfs:label
  • Prednisolone
rdfs:comment
  • Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Prednisolone can also be used as an immunosuppressive drug for organ transplants and in cases of adrenal insufficiency (Addison's).
  • Prednisolone is a steroid. It is used for many conditions including allergies, inflammatory diseases, autoimmune diseases and some forms of cancer. One of its primary benefits is that it can be administered in several different ways depending on the tolerance of the patient and the condition to be treated. In addition to being administered by injection, it can also be taken orally, used in a skin cream, and even put into eye drops.
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dcterms:subject
dbkwik:babyish/pro...iPageUsesTemplate
ChEMBL
  • 131(xsd:integer)
verifiedrevid
  • 477172058(xsd:integer)
excretion
  • Prednisolone is excreted via urine
StdInChIKey
  • OIGNJSKKLXVSLS-VWUMJDOOSA-N
ATC prefix
  • A07
legal US
  • Rx-only
legal UK
  • POM
pregnancy TW
  • C/D
molecular weight
  • 360(xsd:double)
InChIKey
  • OIGNJSKKLXVSLS-VWUMJDOOBF
IUPAC name
  • -111721(xsd:integer)
PubChem
  • 5755(xsd:integer)
CAS number
  • 50(xsd:integer)
H
  • 28(xsd:integer)
InChI
  • 1(xsd:integer)
pregnancy AU
  • A
MedlinePlus
  • a682794
Verifiedfields
  • changed
smiles
  • O=C\1\C=C/[C@]4C
ChemSpiderID
  • 5552(xsd:integer)
ATC suffix
  • EA01
pregnancy US
  • C
elimination half-life
  • -10800.0
Image
  • Prednisolone-3D-balls.png
UNII
  • 9(xsd:integer)
synonyms
  • (11,17-dihydroxy-17- - 10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17- dodecahydrocyclopenta [a]phenanthren-3-one)
ATC supplemental
  • , , , , , , ,
DrugBank
  • APRD00197
StdInChI
  • 1(xsd:integer)
KEGG
  • D00472
ChEBI
  • 8378(xsd:integer)
O
  • 5(xsd:integer)
C
  • 21(xsd:integer)
abstract
  • Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Prednisolone can also be used as an immunosuppressive drug for organ transplants and in cases of adrenal insufficiency (Addison's). Corticosteroids inhibit the inflammatory response to a variety of inciting agents and, it is presumed, delay or slow healing. They inhibit the edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation with inflammation.
  • Prednisolone is a steroid. It is used for many conditions including allergies, inflammatory diseases, autoimmune diseases and some forms of cancer. One of its primary benefits is that it can be administered in several different ways depending on the tolerance of the patient and the condition to be treated. In addition to being administered by injection, it can also be taken orally, used in a skin cream, and even put into eye drops. It's typical side effects are nausea and sedation. However, in about 5% of patients, it can lead to psychiatric problems. With long term use, it can cause bone loss, weakness, yeast infections and easy bruising.
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