About: Waldenström's macroglobulinemia   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : 134.155.108.49:8890 associated with source dataset(s)

Waldenstrom's macroglobulinemia is a form of cancer that causes the unrestricted production of B cells. These interfere with the production of red blood cells, which leads to anemia. They also produce immunoglobulin which thickens the blood, making clotting more likely. It is extremely rare with only about 1,500 cases diagnosed per year in the United States. It can be caused by faults in one of several genes. Care must be taken to do a differential diagnosis to rule out diseases such as multiple myeloma and non-Hodgkin's lymphoma, both of which have similar symptoms.

AttributesValues
rdfs:label
  • Waldenström's macroglobulinemia
rdfs:comment
  • Waldenstrom's macroglobulinemia is a form of cancer that causes the unrestricted production of B cells. These interfere with the production of red blood cells, which leads to anemia. They also produce immunoglobulin which thickens the blood, making clotting more likely. It is extremely rare with only about 1,500 cases diagnosed per year in the United States. It can be caused by faults in one of several genes. Care must be taken to do a differential diagnosis to rule out diseases such as multiple myeloma and non-Hodgkin's lymphoma, both of which have similar symptoms.
sameAs
dcterms:subject
mortalityrate
  • 3.15576E8
symptom
  • Weakness, fatigue, weight loss, oozing blood from nose and gums.
dbkwik:house/prope...iPageUsesTemplate
Name
  • Waldenstrom's macroglobulinemia
Type
treatment
Cause
  • Uncontrolled increase of B cells
abstract
  • Waldenstrom's macroglobulinemia is a form of cancer that causes the unrestricted production of B cells. These interfere with the production of red blood cells, which leads to anemia. They also produce immunoglobulin which thickens the blood, making clotting more likely. It is extremely rare with only about 1,500 cases diagnosed per year in the United States. It can be caused by faults in one of several genes. Care must be taken to do a differential diagnosis to rule out diseases such as multiple myeloma and non-Hodgkin's lymphoma, both of which have similar symptoms. The disease cannot be cured, but can be treated. However, if the condition is largely asymptomatic, the patient should merely be monitored in the event they start developing symptoms as the treatments are invasive, such as chemotherapy, steroids and plasmapheresis.
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