Rigellian plague was a disease prevalent on Rigel II. It was a strain of Kassaba fever, but had a number of different symptoms that made it difficult to identify when it was first discovered afflicting Rigel II. Its victims died in a slow agony. It decimated a quarter of Rigel II's population. Rigellian plague may be the same illness as the "Rigelian Kassaba fever" mentioned by Leonard McCoy in a false diagnosis in the TOS episode: "By Any Other Name".
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