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| - Neo Periwinkle Cortex, (ネオ・コルテックス Neo Cortex in Japanese) most known as Doctor Neo Cortex, N. Cortex, Cortex, or Doctor Cortex, is a professional evil scientist born in Peoria, Illinois and the main antagonist of the Crash Bandicoot series. He is known as the creator of his nemesis: Crash Bandicoot. In almost all games, Cortex is usually the final boss, the exception being N-Tranced (where he is a playable character in multiplayer mode), Crash Tag Team Racing (where he is a playable character), Crash Twinsanity (where he is the first boss and then becomes a playable character in some levels) and Crash of the Titans (where he is also the first boss).
- In the series, Cortex is depicted as a mad scientist who seeks to achieve world domination as an act of vengeance for the ridicule he has suffered in the past. Hoping to achieve this by mutating the local animals into his soldiers, he eventually creates Crash Bandicoot, the titular character of the series, but soon rejects him as unworthy of being in his army and removes him from his castle. As Cortex's actions endanger the sanctity of the islands the games are set in, Cortex's plans for world domination are often hampered by Crash along with other characters. Crash's constant interference has made eliminating Crash one of Cortex's top priorities along with world domination.
- Doctor Neo Cortex, often shortened to N. Cortex, Doctor Cortex, or just simply Cortex, is a video game character and main antagonist of the Crash Bandicoot series. He has directly appeared in all the Crash Bandicoot games thus far except Crash Bandicoot 2: N-Tranced for Game Boy Advance, although he is mentioned by name and is a playable character in the two-player mode if it is linked up to Crash Bandicoot: The Huge Adventure.
- Doctor Neo Periwinkle Cortex, often referred to as "Doctor Cortex" or simply "Cortex", is a video game character and the primary antagonist of the Crash series of video games. He was originally designed by Charles Zembillas and Joe Pearson.
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