About: Conn's syndrome

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About two-thirds of cases are caused by an enlargement of the adrenal glands, while the majority of the remainder are caused by a tumor on the adrenals. More rarely, it is caused by adrenal cancer or by a genetic condition. About 10% of patients with high blood pressure also have Conn's. It is more common in women, and usually is first diagnosed in patients over 30 but under 50. In addition, about 40% of patients have been identified with a common gene even in non-genetic cases.

Attributes	Values
rdfs:label	Conn's syndrome
rdfs:comment	About two-thirds of cases are caused by an enlargement of the adrenal glands, while the majority of the remainder are caused by a tumor on the adrenals. More rarely, it is caused by adrenal cancer or by a genetic condition. About 10% of patients with high blood pressure also have Conn's. It is more common in women, and usually is first diagnosed in patients over 30 but under 50. In addition, about 40% of patients have been identified with a common gene even in non-genetic cases.
dcterms:subject	Diseases Endocrinology
mortalityrate	Low
symptom	High blood pressure, poor vision, headaches, muscle weakness, spasms, tingling sensation, excess urination
dbkwik:house/prope...iPageUsesTemplate	dbkwik:resource/2pprzMEqwVk7gNVcrxanIg==
Name	Primary aldosteronism or Conn's syndrome
Type	Endocrinology
treatment	Spironolactone Eplerenone
Cause	Most commonly, enlargement of the adrenal glands
abstract	About two-thirds of cases are caused by an enlargement of the adrenal glands, while the majority of the remainder are caused by a tumor on the adrenals. More rarely, it is caused by adrenal cancer or by a genetic condition. About 10% of patients with high blood pressure also have Conn's. It is more common in women, and usually is first diagnosed in patients over 30 but under 50. In addition, about 40% of patients have been identified with a common gene even in non-genetic cases. The condition can only be accurately diagnosed by measuring the ratio of aldosterone in the blood to the level of renin, an enzyme. The condition is typified by a very high ratio between the two. In most cases, medical imaging is performed to pinpoint the cause. Treatment depends on the underlying cause. If a tumor is the cause, surgical removal is recommended. If only one adrenal gland is enlarged, it is usually removed. However, if both are enlarged, drug therapy is usually recommended.

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