* Francine looks for Stan's sperm and finds a sperm sample for Janet Reno, who is a woman.
* The Knack's "My Sharona" plays as Stan tries to stop Francine.
* Roger sings Bing Crosby's "Moonlight Becomes You" while being held captive.
* Stan compares Steve with the fall of Saigon. In his analogy, Francine's uterus represents Saigon and Steve's birth represents the "last chopper out".
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* During Stan's post-vasectomy sex, he mentions a position called the "Reverse Bulldog" to Francine, adding that she needs to punch him harder. The Reverse Bulldog is commonly known as a wrestling move.
* When Roger reveals to Ethan he's not really a professor, he says he prefers to return to his old life of watching bad television. Both The Majestic and Ace Ventura he mentions starred Jim Carrey. Seth MacFarlane was a writer for the cartoon adaptation of Ace Ventura. In another Jim Carrey connection, the scene of Stan and Francine having sex in the trunk of the car is similar to a scene in Jim Carrey's Once Bitten of making love in a casket.
* Debbie identifies Stan's gun as a Kel-Tec P-11 9mm.