Scopolamine (also referred to as hyoscine hydrobromide or scopolamine hydrobromide) is a drug used for motion sickness. Scopolamine Structure.png|Scopolamine structure
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| - Scopolamine (also referred to as hyoscine hydrobromide or scopolamine hydrobromide) is a drug used for motion sickness. Scopolamine Structure.png|Scopolamine structure
- Scopolamine, also known as hyoscine, is a tropane alkaloid drug with muscarinic antagonist effects. It is obtained from plants of the family Solanaceae (nightshades), such as henbane, jimson weed and Angel's Trumpets (Datura resp. Brugmansia spec.), and corkwood (Duboisia species [1]). It is among the secondary metabolites of these plants. Therefore, scopolamine is one of three active components of belladonna and stramonium tinctures and powders used medicinally along with atropine and hyoscyamine.
- Scopolamine, also known as levo-duboisine, and hyoscine, is a tropane alkaloid drug with muscarinic antagonist effects. It is obtained from plants of the family Solanaceae (nightshades), such as henbane, jimson weed and Angel's Trumpets (Datura resp. Brugmansia spec.), and corkwood (Duboisia species ). It is among the secondary metabolites of these plants. Therefore, scopolamine is one of three main active components of belladonna and stramonium tinctures and powders used medicinally along with atropine and hyoscyamine. Scopolamine was isolated from plant sources by scientists in 1881 in Germany and description of its structure and activity followed shortly thereafter.
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| - 303(xsd:integer)
- 303(xsd:double)
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| - --3-Hydroxy-2-phenyl-propionic acid -9-methyl-3-oxa-9-aza-tricyclo[3.3.1.02,4]non-7-yl ester
- --3-Hydroxy-2-phenyl-propionic acid -9-methyl-3-oxa-9-aza-tricyclo[3.3.1.02,4]non-7-yl ester
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| routes of administration
| - transdermal, ocular, oral, subcutaneous, intravenous
- transdermal, ocular, oral, subcutaneous, intravenous, sublingual, rectal, buccal transmucousal, intramuscular
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| abstract
| - Scopolamine, also known as levo-duboisine, and hyoscine, is a tropane alkaloid drug with muscarinic antagonist effects. It is obtained from plants of the family Solanaceae (nightshades), such as henbane, jimson weed and Angel's Trumpets (Datura resp. Brugmansia spec.), and corkwood (Duboisia species ). It is among the secondary metabolites of these plants. Therefore, scopolamine is one of three main active components of belladonna and stramonium tinctures and powders used medicinally along with atropine and hyoscyamine. Scopolamine was isolated from plant sources by scientists in 1881 in Germany and description of its structure and activity followed shortly thereafter. Scopolamine has anticholinergic properties and has legitimate medical applications in very minute doses. As an example, in the treatment of motion sickness, the dose, gradually released from a transdermal patch, is only 330 microgrammes (µg) per day. In rare cases, unusual reactions to ordinary doses of scopolamine have occurred including confusion, agitation, rambling speech, hallucinations, paranoid behaviors, and delusions.
- Scopolamine (also referred to as hyoscine hydrobromide or scopolamine hydrobromide) is a drug used for motion sickness. Scopolamine Structure.png|Scopolamine structure
- Scopolamine, also known as hyoscine, is a tropane alkaloid drug with muscarinic antagonist effects. It is obtained from plants of the family Solanaceae (nightshades), such as henbane, jimson weed and Angel's Trumpets (Datura resp. Brugmansia spec.), and corkwood (Duboisia species [1]). It is among the secondary metabolites of these plants. Therefore, scopolamine is one of three active components of belladonna and stramonium tinctures and powders used medicinally along with atropine and hyoscyamine. Scopolamine has anticholinergic properties and has legitimate medical applications in very minute doses. As an example, in the treatment of motion sickness, the dose, gradually released from a transdermal patch, is only 330 micrograms (µg) per day. An overdose can cause delirium, delusions, paralysis , dangerous elevations of body temperature, stupor and death.
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