About: Muckle-Wells syndrome

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Muckle-Wells syndrome is a rare genetic disease where a body overproduces a protein used to indicate trauma or infection. As a result, the immune system is fooled into believing such conditions exist and produces interleukin, which is responsible for inflammation. This inflammation eventually causes damage to the nerves leading to the ear responsible for hearing and the joints (similar to arthritis). It also causes widespread hives. The inflammation can also lead to secondary amyloidosis.

Attributes	Values
rdfs:label	Muckle-Wells syndrome
rdfs:comment	Muckle-Wells syndrome is a rare genetic disease where a body overproduces a protein used to indicate trauma or infection. As a result, the immune system is fooled into believing such conditions exist and produces interleukin, which is responsible for inflammation. This inflammation eventually causes damage to the nerves leading to the ear responsible for hearing and the joints (similar to arthritis). It also causes widespread hives. The inflammation can also lead to secondary amyloidosis.
dcterms:subject	Diseases Genetics
mortalityrate	Low
symptom	Deafness, fever, chills, hives, painful joints
dbkwik:house/prope...iPageUsesTemplate	dbkwik:resource/2pprzMEqwVk7gNVcrxanIg==
Appearances	Recession Proof
Name	Muckle-Wells syndrome
Type	Genetic
treatment	Canakinumab Anakinra Rilonacept
Cause	Increased production of NALP3
abstract	Muckle-Wells syndrome is a rare genetic disease where a body overproduces a protein used to indicate trauma or infection. As a result, the immune system is fooled into believing such conditions exist and produces interleukin, which is responsible for inflammation. This inflammation eventually causes damage to the nerves leading to the ear responsible for hearing and the joints (similar to arthritis). It also causes widespread hives. The inflammation can also lead to secondary amyloidosis. Unlike most diseases that cause inflammation, Muckle-Wells requires a more targeted approach. The drugs used for the condition are those that interfere with the production of interleukin, reducing the cause of the inflammation.
is diagnosis of	Recession Proof

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