For the five days the shuttle was docked to Mir they were the largest spacecraft in orbit at the time. STS-71 marked the first docking of a space shuttle to a space station, the first time a shuttle crew switched members with the crew of a station, and the 100th manned space launch by the United States. The mission carried Spacelab and included a logistical resupply of Mir. Together the shuttle and station crews conducted various on-orbit joint US/Russian life science investigations with Spacelab along with the Shuttle Amateur Radio Experiment-II (SAREX-II) experiment.