About: Glucagonoma   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : 134.155.108.49:8890 associated with source dataset(s)

Because glucagon increases the level of blood sugar by breaking down fat, protein and amino acids. This leads to anemia, diarrhea and rapid weight loss. An associated paraneoplastic syndrome, necrolytic migratory erythema, causes widespread blisters and edema. Patients usually develop the symptoms of diabetes mellitus, although the etiology is different. The disease is usually diagnosed by the presence of very high levels of glucagon in the blood, but many patients show only elevated levels.

AttributesValues
rdfs:label
  • Glucagonoma
rdfs:comment
  • Because glucagon increases the level of blood sugar by breaking down fat, protein and amino acids. This leads to anemia, diarrhea and rapid weight loss. An associated paraneoplastic syndrome, necrolytic migratory erythema, causes widespread blisters and edema. Patients usually develop the symptoms of diabetes mellitus, although the etiology is different. The disease is usually diagnosed by the presence of very high levels of glucagon in the blood, but many patients show only elevated levels.
sameAs
dcterms:subject
mortalityrate
  • High
symptom
  • Decreased blood levels of amino acids, anemia, diarrhea, weight loss
dbkwik:house/prope...iPageUsesTemplate
Name
  • Glucagonoma
Type
treatment
Cause
  • Uncontrolled growth of alpha cells in the pancreas
abstract
  • Because glucagon increases the level of blood sugar by breaking down fat, protein and amino acids. This leads to anemia, diarrhea and rapid weight loss. An associated paraneoplastic syndrome, necrolytic migratory erythema, causes widespread blisters and edema. Patients usually develop the symptoms of diabetes mellitus, although the etiology is different. The disease is usually diagnosed by the presence of very high levels of glucagon in the blood, but many patients show only elevated levels. Although surgery is the only possibily of a cure, the symptoms can be controlled with drugs that inhibit glucagon production or damage the pancreatic cells that create glucagon.
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