The Drakh plague is the name given to a bio-genetic nano-virus actually developed by the Shadows and inherited by their Drakh servants when they and the other First Ones left the galaxy in 2261, following the Battle of Coriana VI. The nano-virus works by intelligently adapting itself to the species that it has infected. After that it is simply a matter of time before it finds the right trigger to kill the entire species outright.
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