About: Neuroligins   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : 134.155.108.49:8890 associated with source dataset(s)

Neuroligins are a family of proteins that are known to be mutated in some patients with autism. Along with the neurexin proteins, neuroligins are involved in the synapses which allow information to travel between cells in the nervous system. Study co-author Palmer Taylor says that understanding the mutations in these proteins may explain some of the early behavioral abnormalities associate with autism spectrum disorders: "Abnormal synaptic development in nerve connections is likely to lead to cognitive deficits seen in patients with autism."

AttributesValues
rdfs:label
  • Neuroligins
rdfs:comment
  • Neuroligins are a family of proteins that are known to be mutated in some patients with autism. Along with the neurexin proteins, neuroligins are involved in the synapses which allow information to travel between cells in the nervous system. Study co-author Palmer Taylor says that understanding the mutations in these proteins may explain some of the early behavioral abnormalities associate with autism spectrum disorders: "Abnormal synaptic development in nerve connections is likely to lead to cognitive deficits seen in patients with autism."
dcterms:subject
abstract
  • Neuroligins are a family of proteins that are known to be mutated in some patients with autism. Along with the neurexin proteins, neuroligins are involved in the synapses which allow information to travel between cells in the nervous system. In June 2007, a study was published in the journal Structure which mapped the structure of the neuroligin/β-neurexin complex. Researchers from the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences, led by Davide Comoletti, Ph.D., found clues in this mapping that may help scientists to understand the effects of mutations in these proteins. Study co-author Palmer Taylor says that understanding the mutations in these proteins may explain some of the early behavioral abnormalities associate with autism spectrum disorders: "Abnormal synaptic development in nerve connections is likely to lead to cognitive deficits seen in patients with autism." The study's findings may lead to new leads in for autism spectrum disorders.
Alternative Linked Data Views: ODE     Raw Data in: CXML | CSV | RDF ( N-Triples N3/Turtle JSON XML ) | OData ( Atom JSON ) | Microdata ( JSON HTML) | JSON-LD    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3217, on Linux (x86_64-pc-linux-gnu), Standard Edition
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2012 OpenLink Software