According Onwa Hikaeme, the Purification Release's most notable carrier, this Kekkei Tōta was responsible for the first medical jutsus' creation. There is also a legend that this technique was also used by Hagoromo Ōtsutsuki's wife, however with the passage of time it has been becoming a less famous and known technique and thus lost the relationship between the Purification Release and the Sage of the Six Paths' wife.
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