USS Waccamaw (AO-109) was a replenishment oiler in the United States Navy. She was named after Waccamaw River. The original capacity was . Waccamaw was laid down on 28 April 1945 by the Sun Shipbuilding and Drydock Co., Chester, Pennsylvania; launched on 30 March 1946; sponsored by Miss Irene F. Long; and commissioned on 25 June 1946, Capt. Guy W. Stringer in command. It was the last of five oilers in the Mispillion class.