The extinction occurred 443.8 million years ago, during the Great Ordovician Biodiversification Event.[7] It marks the boundary between the Ordovician and following Silurian period. During this extinction event there were several marked changes in biologically responsive carbon and oxygen isotopes. This complexity may indicate several distinct closely spaced events, or particular phases within one event. Statistical analysis of marine losses at this time suggests that the decrease in diversity was mainly caused by a sharp increase in extinctions, rather than a decrease in speciation.
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