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| - First seen during the 1930s in a supporting role in Hatlo's popular gag panel, They'll Do It Every Time, Little Iodine was the daughter of Henry Tremblechin and his wife, Cora. Her purpose was to serve as a pesky nuisance to the strip's star, Henry, and her behavior caused endless misery for her mild-mannered, easily unsettled father. Al Scaduto also contributed to the strip in 1966, with Hy Eisman and Bob Dunn taking the strip from 1967 through its end in 1985. Iodine also appeared in a series of 56 Dell Comics between 1949 and 1962.
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| - First seen during the 1930s in a supporting role in Hatlo's popular gag panel, They'll Do It Every Time, Little Iodine was the daughter of Henry Tremblechin and his wife, Cora. Her purpose was to serve as a pesky nuisance to the strip's star, Henry, and her behavior caused endless misery for her mild-mannered, easily unsettled father. However, Iodine proved to be popular in her own right, stealing the strip from her parents, so Hatlo promoted the character into her own strip in 1943. Iodine's antics gave the Sunday comics page a female precursor to Hank Ketcham's Dennis the Menace. From 1943 to 1963, Little Iodine was written and drawn by Hatlo, who said, "I tried to make her the embodiment of all the brats I knew... I tried to make her naughty as hell—and still likable." Al Scaduto also contributed to the strip in 1966, with Hy Eisman and Bob Dunn taking the strip from 1967 through its end in 1985. Iodine also appeared in a series of 56 Dell Comics between 1949 and 1962.
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