Estradiol valerate (INN, USAN; brand names Altadiol, Deladiol, Delestrogen, Estraval, Progynova, Valergen, many others), or oestradiol valerate (BAN), is a synthetic ester, specifically the 17-pentanoyl ester, of the natural estrogen, estradiol. It was introduced in the 1950nd, and along with estradiol benzoate and estradiol cypionate, has since become one of the most widely used esters of estradiol. Compared to estradiol, estradiol esters such as estradiol valerate are absorbed more slowly and possess longer half-lives, and as a result, can be administered less frequently.
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