About: Primary sclerosing colangitis   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : 134.155.108.49:8890 associated with source dataset(s)

Primary sclerosing colangitis is a serious liver disease characterized by scarring, inflammation and blockages of the bile ducts. Bile becomes unable to leave the liver, resulting in cirrhosis, liver failure and on occasion, liver cancer. The condition also interferes with the absorption of several fat soluble vitamins, resulting in symptoms of malnutrition. It is not clearly known what causes colangitis, but often arises in patients with inflammatory bowel disease and ulcerative colitis.

AttributesValues
rdfs:label
  • Primary sclerosing colangitis
rdfs:comment
  • Primary sclerosing colangitis is a serious liver disease characterized by scarring, inflammation and blockages of the bile ducts. Bile becomes unable to leave the liver, resulting in cirrhosis, liver failure and on occasion, liver cancer. The condition also interferes with the absorption of several fat soluble vitamins, resulting in symptoms of malnutrition. It is not clearly known what causes colangitis, but often arises in patients with inflammatory bowel disease and ulcerative colitis.
dcterms:subject
mortalityrate
  • About 15%, depending on treatment
symptom
  • Fatigue, jaundice, cirrhosis, pale stool, darkened urine
dbkwik:house/prope...iPageUsesTemplate
Name
  • Primary sclerosing colangitis
Type
  • Unknown for certain, but appears to be autoimmune
treatment
abstract
  • Primary sclerosing colangitis is a serious liver disease characterized by scarring, inflammation and blockages of the bile ducts. Bile becomes unable to leave the liver, resulting in cirrhosis, liver failure and on occasion, liver cancer. The condition also interferes with the absorption of several fat soluble vitamins, resulting in symptoms of malnutrition. It is not clearly known what causes colangitis, but often arises in patients with inflammatory bowel disease and ulcerative colitis. Colangitis proceeds extremely slowly, and a patient who is developing the disease may not show symptoms for years. It is usually diagnosed in persons between the ages of 30 and 60, and is more common in men than in women.
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