About: Mefenamic acid

Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Mefenamic acid Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : 134.155.108.49:8890 associated with source dataset(s)

Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. It is typically prescribed for oral administration. Mefenamic acid decreases inflammation (swelling) and uterine contractions by a still unknown mechanism. However it is thought to be related to the inhibition of prostaglandin synthesis.

Attributes	Values
rdfs:label	Mefenamic acid
rdfs:comment	Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. It is typically prescribed for oral administration. Mefenamic acid decreases inflammation (swelling) and uterine contractions by a still unknown mechanism. However it is thought to be related to the inhibition of prostaglandin synthesis.
sameAs	dbr:Mefenamic_acid
dcterms:subject	Medsin dbkwik:resource/HpuNRbF6kreomNTwJMIXKg== dbkwik:resource/xnVWJhmD-CaNU4uoNGemKw==
dbkwik:babyish/pro...iPageUsesTemplate	dbkwik:resource/6-0UkGdbqzNnnadrHtSJ7A== dbkwik:resource/PuU1I_acjSW6iwml7gbOPw== dbkwik:resource/f6yLdd_EQQSqYQDKN1qCQw== dbkwik:resource/YygQKMV58gLDuV7kdsIwlw== dbkwik:resource/hhuyrtkyhS55apMBhaC97g== dbkwik:resource/3XlL0KrTbwLYmsEvfdDmzQ== dbkwik:resource/nXUmgGV5rL97mxXpUQVqWQ== dbkwik:resource/SWo1WFLMqTRqjmr07Pa2UQ== dbkwik:resource/O6WRbg6032BIswPc688-EQ== dbkwik:resource/0TXoo0F7OGzHLf9imMyr_A==
accessdate	2005-09-28(xsd:date)
bioavailability	90.0
verifiedrevid	263877360(xsd:integer)
metabolism	Hepatic 肝臟
excretion	dbkwik:resource/V-vgoIqp1fa1QLdWkrQkXw== Renal and fecal
ATC prefix	M01
Legal Status	℞-only , POM in UK
N	1(xsd:integer)
molecular weight	241(xsd:double)
protein bound	90.0
Language	en
IUPAC name	2(xsd:integer)
PubChem	4044(xsd:integer)
CAS number	61(xsd:integer)
H	15(xsd:integer)
pregnancy category	C
ChemSpiderID	3904(xsd:integer)
ATC suffix	AG01
elimination half-life	2(xsd:integer) 7200.0
url	http://cardiology.jwatch.org/cgi/content/full/2002/315/3\|title=NSAIDs May Increase Risk for Worsening Heart Failure(en) http://archinte.ama-assn.org/cgi/content/abstract/160/6/777\|title=Consumption of NSAIDs and the Development of Congestive Heart Failure in Elderly Patients(en) http://www.rxlist.com/cgi/generic3/mefenamic_cp.htm\|title=Ponstel Pharmacology, Pharmacokinetics, Studies, Metabolism - Mefenamic Acid - RxList Monographs(en) http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a681028.html\|title=MedlinePlus Drug Information: Mefenamic Acid(en)
Watchedfields	changed
DrugBank	APRD0073
routes of administration	Oral 口服
O	2(xsd:integer)
C	15(xsd:integer)
abstract	Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain. It is typically prescribed for oral administration. Mefenamic acid decreases inflammation (swelling) and uterine contractions by a still unknown mechanism. However it is thought to be related to the inhibition of prostaglandin synthesis. Since hepatic metabolism plays a significant role in mefenamic acid elimination, patients with known liver deficiency may be prescribed lower doses. Kidney deficiency may also cause accumulation of the drug and its metabolites in the excretory system. Therefore patients suffering from renal conditions should not be prescribed mefenamic acid.

OpenLink Virtuoso version 07.20.3217, on Linux (x86_64-pc-linux-gnu), Standard Edition
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2012 OpenLink Software