The basic model used when describing an enzyme and substrate complex is the 'lock and key' model. This is based around the notion that a substrate fits into the enzyme's binding region like a unique key fitting a lock, leading to the breakdown of the substrate into products. Different bonds can be formed between the enzyme and substrate e.g. ionic bonds, disulphide bridges and Van Der Waal's forces. These facilitate the initial binding of the enzyme and substrate.
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