Santa Cabeza (literally translating as "Saint Head") is the fictional Central American town which is frequently referred to in the Dead Rising video game. It is the origin of the Ampulex Compressa Giganteus and the town where Dr. Russell Barnaby's former research laboratory was based. The town was destroyed by the accidental zombie outbreak and the subsequent cleanup operation led by Brock Mason and the Special Forces, in what is now called the Santa Cabeza Incident. Carlito and Isabela Keyes lived in this town and saw their loved ones killed.
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