The Residual Poison was an innovation attributed to the Mentat Piter de Vries. It was a substance which could be impregnated into a victim, whereby the victim must receive the antidote repeatedly. Withdrawal of the antidote at any time would bring death after several days. The Baron Vladimir Harkonnen bestowed this poison onto Thufir Hawat, who died of it when Shaddam IV was defeated on Arrakis.
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