About: Subacute sclerosing panencephalitis   Sponge Permalink

An Entity of Type : owl:Thing, within Data Space : 134.155.108.49:8890 associated with source dataset(s)

Subacute sclerosing panencephalitis is a very rare complication of measles, occurring about once in every 100,000 cases of measles. In most patients, measles contracted at any age results in immunity to the disease indefinitely. However, in some patients who contract the disease before the age of two whose mothers had no immunity to the disease, the disease goes through an initial acute phase, then develops into a latent stage. Certain of the measles viruses then undergo a mutation which renders them impervious to the body's immune system. After about 6-15 years, the latent virus starts attacking the body's nervous system, particularly the spinal cord and the brain, resulting in severe neurological symptoms.

AttributesValues
rdfs:label
  • Subacute sclerosing panencephalitis
rdfs:comment
  • Subacute sclerosing panencephalitis is a very rare complication of measles, occurring about once in every 100,000 cases of measles. In most patients, measles contracted at any age results in immunity to the disease indefinitely. However, in some patients who contract the disease before the age of two whose mothers had no immunity to the disease, the disease goes through an initial acute phase, then develops into a latent stage. Certain of the measles viruses then undergo a mutation which renders them impervious to the body's immune system. After about 6-15 years, the latent virus starts attacking the body's nervous system, particularly the spinal cord and the brain, resulting in severe neurological symptoms.
sameAs
dcterms:subject
mortalityrate
  • High. Inevitably fatal if untreated.
symptom
  • Double vision, myoclonic jerk, fever, personality change, seizures, lack of coordination, sensitivity to light,
dbkwik:house/prope...iPageUsesTemplate
Appearances
Name
  • Subacute sclerosing panencephalitis
Type
  • Infection
treatment
  • Direct injection of medication into the cerebro-spinal fluid
Cause
  • Incomplete recovery from measles infection in an infant
abstract
  • Subacute sclerosing panencephalitis is a very rare complication of measles, occurring about once in every 100,000 cases of measles. In most patients, measles contracted at any age results in immunity to the disease indefinitely. However, in some patients who contract the disease before the age of two whose mothers had no immunity to the disease, the disease goes through an initial acute phase, then develops into a latent stage. Certain of the measles viruses then undergo a mutation which renders them impervious to the body's immune system. After about 6-15 years, the latent virus starts attacking the body's nervous system, particularly the spinal cord and the brain, resulting in severe neurological symptoms. The disease must be treated soon after symptoms begin to appear, otherwise the course of the disease is terminal (similar to rabies).
is diagnosis of
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