In The Cleveland-Loretta Quagmire, together with Peter Griffin, they delivered a devastating diagnosis to a hospital patient named Mr. Devanney through the song "You Have AIDS". In "Sibling Rivalry" they explain to Peter what a vasectomy entails, in the song "Vasectomy". In Road to the Multiverse they appear in a universe animated by Disney as four singing bees, joining in on a performance of "It’s A Wonderful Day for Pie ". In "Yug Ylimaf", they appear going backwards. They had just gotten back from performing "You Have AIDS".
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