Agent Anne Weaver was the director of S.H.I.E.L.D. Academy of Science and Technology when it was operational.
Anne Weaver is a S.H.I.E.L.D. agent. She served as the director of S.H.I.E.L.D. Academy of Science and Technology for years until HYDRA revealed its existence to the world and attacked S.H.I.E.L.D. She managed to survive the Battle at the S.H.I.E.L.D. Academy and joined the remains of S.H.I.E.L.D. led by Robert Gonzales. When another faction of S.H.I.E.L.D. led by Phil Coulson emerged, Weaver supported the attack on it. After the reunification of S.H.I.E.L.D., she became one of Director Coulson's advisors.
Agent Anne Weaver was the head of the Science and Technology division of S.H.I.E.L.D. Academy, before HYDRA was discovered to be lurking within S.H.I.E.L.D. In "Seeds" she is seen meeting with Agent Coulson's team in order to help them locate the Atmospheric Moisture Freezing Device developed by one of the students at the academy. In "Turn, Turn, Turn" she also makes an appearance, warning Agent Simmons of S.H.I.E.L.D's compromise, telling her not to trust anyone. She returns in "Love in the Time of Hydra" as a key part of the "real S.H.I.E.L.D.".