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| - La Dra. Poofenplotz (Profesora Poofenploz en España) es la némesis, o enemiga, de Pinky, el/la Chihuahua. Está involucrada a muchos problemas, busca una dotacion ilimitada de belleza tiesa en el parque de diversiones abandonado. En La Montaña Rusa el Musical durante la canción Carpe Diem se ve en la Pantalla en la que debería estar la Comandante Wanda Acronym. Reaparece en Excaliferb. En “Una historia con abejas” se supo que trató de ser parte de M.E.R.M.E.L.A.D.A., que fue cancelada.
- Esmeralda Poofenplotz, more commonly known as Professor Poofenplotz, is a local mad scientist and the nemesis of Agent Pinky, Isabella Garcia-Shapiro's dog. ("Day of the Living Gelatin", "Isabella and the Temple of Sap, "Bee Story")
- Esmeralda Poofenplotz, được biết đến nhiều với tên Giáo sư Poofenplotz, là một tiến sĩ khoa học điên rồ và là kẻ thù của Đặc vụ Pinky, cún của Isabella Garcia-Shapiro. ("Day of the Living Gelatin", "Isabella and the Temple of Sap", "Bee Story")
- Professor Esmeralda Poofenplotz is a recurring antagonist in the Disney animated show, Phineas and Ferb. She is the nemesis of Pinky, Isabella Garcia-Shapiro's pet chihuahua. She was first mentioned in "Day of the Living Gelatin", later appearing in "Isabella and the Temple of Sap" and "Bee Story" as the main antagonist. She was voiced by recurring guest star Amanda Plummer.
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