A French Jew and colonel and chief intelligence officer in the French army that works with the Qing Bang. Although he has mastered Hokuto Sonkaken, he prefers using conventional fighting methods like guns and swords, irritating even the likes of Mang Kuang-Yun at one point. He has a sister, Sophie, who suffered trauma resulting in memory suppression due to her experiences in escaping from Nazi Germany as her husband (a non-Jewish German who was prohibited from marrying her by Nazi law) got sent to a concentration camp. When she regained her memory by Kenshiro's acupressure, she was assassinated by Zhang Tai-Yan. De Guise was eventually wounded fatally by Liú Fēi-Yàn when the latter deemed him unfit to take care of Erika Arendt and challenged him to a duel. Kenshiro used acupressure techni