Louis Brian Piccolo (October 31, 1943 – June 16, 1970) was a professional football player for the Chicago Bears for four years. He died from embryonal cell carcinoma, an aggressive form of germ cell testicular cancer, first diagnosed after it had spread to his chest cavity. He was the subject of the 1971 TV movie Brian's Song, with a remake (of the same title) TV movie filmed in 2001. Piccolo was portrayed in the original film by James Caan and by Sean Maher in the 2001 remake.