On May 12, 2001, Burnett recorded a no-hitter in a complete game shut-out against the San Diego Padres in his second start of the season. He shut down the Padres with the 3-0 victory even after issuing nine walks, helping his own cause by striking out seven Padres hitters. His game-worn cap and a baseball from the game are on display at the National Baseball Hall of Fame and Museum in Cooperstown, New York.