HMS Illustrious, a 74-gun third rate ship of the line and the second of that name, was built by Randall & Brent at Rotherhithe where her keel was laid in February 1801. Launched on 3 September 1803, she was completed at Woolwich. She was first commissioned for the Channel Fleet under Captain Sir Charles Hamilton and was involved in the Battle of the Basque Roads in 1809, in which she won a battle honour, and in the expeditions against the docks at Antwerp and render the Schelde unnavigable to French ships. On 22 November 1810, Illustrious was amongst the fleet that overtook Mauritius on 3 December. She then took part in the Invasion of Java (1811) in Indonesia. She was refitted at Portsmouth (1813–17) and then laid up in reserve until recommissioned in 1832. She was laid up again in 1845,