In 2269, the crew of Federation starship USS Enterprise became infected with Rigelian fever and visited the planet Holberg 917G, which had rich natural ryetalyn deposits. There they encountered the immortal Flint and his android partner Rayna Kapec. (TOS: "Requiem for Methuselah" ) In the Roswell episode "Secrets and Lies", Max Evans auditions for a role in a fictional episode of Star Trek: Enterprise directed by Jonathan Frakes in which the Enterprise crew have contracted Rigelian fever and Doctor Phlox must obtain ryetalyn to cure them.