The 2009–10 Mercyhurst Lakers women's ice hockey team represented Mercyhurst College in the 2009–10 NCAA Division I women's ice hockey season. The Lakers were coached by Michael Sisti. Assisting Sisti are Paul Colontino and Louis Goulet. Mike Folga was the Head Equipment Manager. The Lakers will attempt to qualify for the NCAA Women's Frozen Four for the second consecutive season. Vicki Bendus, Bailey Bram and Jesse Scanzano were all Top-10 finalists for the Patty Kazmaier Award. This marked only the third time in NCAA history (Harvard: 1999, Wisconsin: 2009) that one school had three nominees in the Top 10. Bendus was honoured with the award.