After commissioning, USS Wassuc proceeded south; touched at Norfolk, Virginia; and then sailed back northward to the Washington Navy Yard where she arrived on 4 June. She subsequently moved to the Mine Warfare School at Yorktown, Virginia, on 23 June, where she relieved USS Cormorant (AM-40), freeing that minesweeper to begin an overhaul. During her service at Yorktown, Wassuc participated in experimental mine work under the aegis of the Bureau of Ordnance (BuOrd).