USS Biloxi (CL-80) was a United States Navy Cleveland-class light cruiser, the first ship named after the city of Biloxi, Mississippi. The ship was laid down on 9 July 1941 at Newport News, Virginia by the Newport News Shipbuilding & Dry Dock Co. and launched on 23 February 1943, sponsored by Mrs. Katharine G. Braun, wife of the Mayor of Biloxi. She was commissioned at the Norfolk Navy Yard on 31 August 1943, with Captain Daniel M. McGurl in command.