Eugene sells it to Squidward in "Red Mist". This causes Squidward to become insane and try to murder SpongeBob, Patrick, and later Eugene himself. In "Krusty Kourt Kase", Squidward and Eugene are sent to court to see what should be done about the Red Mist incident. In "Reality Squid", the contestants of Seavivor compete to see who can drink the most Red Mist. Squidward wins and begins viciously attacking the contestants . The drug also has an apperance on Plankton Lives With The Raw.