Thabit ibn Nasr ibn Malik al-Khuza'i (died 813/814) was an Abbasid general and governor of the Cilician frontier zone (al-thughur al-Sha'miya) with the Byzantine Empire in 808–813. Thabit was a native of Khurasan, and the grandson of Malik ibn al-Haytham al-Khuza'i, an early Abbasid follower and military leader. He was appointed as governor of the Syrian thughur (essentially comprising Cilicia, with Tarsus as its capital) in the last year of the reign of Harun al-Rashid (808/809). He organized a prisoner exchange with the Byzantines at Podandos in 808, but also led a series of raiding expeditions (sawa'if) against them. In one of these however, in August 812, he suffered a heavy defeat at the hands of Leo the Armenian, losing 2,000 men.