Wesley Duke (born June 21, 1981 in Grand Prairie, Texas) is a football player. Duke was a tight end for the Denver Broncos in the National Football League. He played both basketball and football for the Meadowcreek High School Mustangs in Norcross, Georgia. Duke played NCAA basketball for the Mercer University Bears in Macon, Georgia. Duke graduated from Mercer, and was signed as a free agent to play for the Denver Broncos. Duke tore his knee ligament and was released on June 9, 2006.