Drinking this potion will prevent the player from drinking adrenaline potions for 120 seconds as they share the same cooldown timer, despite that the "Adrenaline potion prevention" debuff does not appear upon drinking super Guthix rest. However, more doses of Super Guthix rest can be drunk during this time for its other effects, allow it to essentially act as a food item that takes more clicks to consume but does not reduce adrenaline, much like Saradomin brews, but heals less, does not affect combat stats, and is much cheaper.