USS Gregory (DD-82/APD-3) was a Wickes-class destroyer in the United States Navy during World War I and, as APD-3 World War II. She was named for Admiral Francis Gregory USN (1780–1866). Gregory was laid down by the Fore River Shipbuilding Company at Quincy, Massachusetts on 25 August 1917, launched on 27 January 1918 by Mrs. George S. Trevor, great-granddaughter of Admiral Gregory, and commissioned on 1 June 1918, Commander Arthur P. Fairfield in command.