The 2006–07 Mercyhurst Lakers women's ice hockey team represented Mercyhurst College in the 2006–07 NCAA Division I women's ice hockey season. The Lakers were coached by Michael Sisti and went 11-0-1 in their conference. Mercyhurst had the second-best scoring defense in Division I in 2006-2007. It would be the rookie season of Meghan Agosta. She was the first freshman ever to be in the Final 3 for the Patty Kazmaier Award. No other freshman had made it that far in voting.