State Highway NASA Road 1 (also NASA Parkway and NASA Road 1) is an east–west state highway that runs from I-Interstate 45 in Webster to State Highway 146 in Seabrook. The route is a 6-lane to 8-lane divided highway for most of its length. A Portion of the route is a 4-lane controlled access highway that bypasses the central businesses of Webster. The highway is the main route to NASA's Lyndon B. Johnson Space Center. It is one of only two Texas highways with an official designation beginning with a letter; the other is State Highway OSR.